Understanding Seroquel High

Unravel the complexities of the Seroquel high, its risks, and long-term effects. Stay informed and make empowered choices.

Leora B.H. Staff

July 31, 2024

Understanding Seroquel Use

To gain a comprehensive understanding of Seroquel, it is important to explore its overview and purpose. Seroquel, also known by its generic name quetiapine, is an atypical antipsychotic drug used to treat serious mental illnesses such as schizophrenia and bipolar disorder in adults and certain children. It belongs to a class of medications known as second-generation antipsychotics.

Overview of Seroquel

Seroquel, or quetiapine, is widely prescribed to individuals with schizophrenia and bipolar disorder. It is available in both brand-name and generic versions. The drug acts by affecting the levels of certain neurotransmitters in the brain, including dopamine and serotonin. By modulating these neurotransmitters, Seroquel helps to alleviate the symptoms associated with these mental health conditions.

Purpose of Seroquel

The primary purpose of Seroquel is to manage the symptoms of schizophrenia and bipolar disorder. It helps to reduce hallucinations, delusions, and disorganized thinking in individuals with schizophrenia. For those with bipolar disorder, Seroquel can help stabilize mood swings, including manic and depressive episodes.

It is important to note that Seroquel is a prescription medication and should only be used under the guidance and supervision of a qualified healthcare professional. The dosage and duration of treatment may vary depending on the individual's specific condition and response to the medication.

While Seroquel has proven to be effective in treating serious mental illnesses, it is essential to understand the potential side effects and risks associated with its use. For more information on the side effects and risks of Seroquel, refer to the section on side effects and risks.

Side Effects and Risks

When considering the use of Seroquel, it's important to be aware of the potential side effects and risks associated with this medication. Seroquel, also known as quetiapine, is an antipsychotic drug commonly prescribed for various mental health conditions. Let's explore the common and serious side effects of Seroquel.

Common Side Effects

Like any medication, Seroquel may cause side effects, although not everyone experiences them. It's essential to be informed about the possible common side effects. These can include:

Dry mouth
Sleepiness
Nasal congestion
Slowed or slurred speech
Increased appetite
Abdominal pain
Weakness
Orthostatic hypotension (drop in blood pressure when standing up)

These common side effects are generally mild and may subside as the body adjusts to the medication. However, if these side effects persist or worsen, it's important to consult a healthcare professional.

It's worth noting that Seroquel XR, an extended-release oral tablet of quetiapine, had certain side effects more commonly reported in clinical trials compared to the immediate-release Seroquel. These side effects include nasal congestion, slowed or slurred speech, and increased appetite [1].

Serious Side Effects

While less common, Seroquel can also cause serious side effects that require immediate medical attention. It's crucial to be aware of these potential risks. Serious side effects of Seroquel include:

Increased blood pressure in children (not reported in adults)
Increased heart rate in children (more common than in adults)
Nausea and vomiting in children (more common than in adults)
Tardive dyskinesia (involuntary movements)
Extrapyramidal symptoms (abnormal muscle movements)
Suicidal thoughts and behaviors, particularly affecting children and young adults (boxed warning)
Increased risk of death in older adults with dementia-related psychosis (boxed warning)

If any of these serious side effects occur, it's essential to seek immediate medical attention. It's worth noting that Seroquel has a boxed warning for the increased risk of death in older adults with dementia-related psychosis and the risk of suicidal thoughts and behaviors, particularly affecting children and young adults [1].

Understanding the potential side effects and risks of Seroquel is crucial for informed decision-making. If you have any concerns or questions about the use of Seroquel, it's important to consult with a healthcare professional. They can provide personalized guidance and address any specific concerns you may have.

In the next sections, we will explore withdrawal symptoms, misuse and abuse of Seroquel, long-term effects, and overdose response. Stay informed to ensure your safety and well-being when using this medication.

Withdrawal from Seroquel

When discontinuing the use of Seroquel (Quetiapine), individuals may experience withdrawal symptoms as their bodies adjust to the absence of the medication. It's important to understand these withdrawal symptoms and how to manage them effectively.

Withdrawal Symptoms

Seroquel withdrawal symptoms can vary from person to person and may include:

Nausea
Vomiting
Restlessness
Abdominal pain
Diarrhea
Muscle rigidity
Irritability
Agitation
Rare cases of withdrawal dyskinesia, characterized by abnormal, involuntary movements of the upper body or facial muscles.

The duration of withdrawal symptoms can also vary. Some individuals may experience symptoms for a few hours, while others may experience them for several weeks. Symptoms that persist beyond six weeks are classified as persistent post-withdrawal symptoms. It's important to note that withdrawal from Seroquel is considered considerably rarer compared to other psychotropic medications [2].

Managing Withdrawal

Managing Seroquel withdrawal should be done under the supervision of a healthcare professional. Tapering the medication is typically recommended, which involves gradually reducing the dosage over a period of months. This allows the body to adjust to the decreasing levels of the medication and minimizes the severity of withdrawal symptoms.

It's important to note that efforts to quantify the prevalence of Seroquel withdrawal are limited due to its rarity. While studies have shown that approximately 48% of participants experienced some withdrawal symptoms from psychotropic medications, the likelihood of Seroquel withdrawal for an individual is difficult to determine [2].

To ensure a safe and successful withdrawal from Seroquel, medical supervision is essential. Healthcare professionals can provide guidance and support throughout the process, monitoring the individual's progress and adjusting the tapering schedule as needed. Regular assessments during the dosage reduction phase can help identify any emerging withdrawal symptoms or complications.

If you or someone you know is considering discontinuing Seroquel, it's crucial to consult with a healthcare professional to develop an individualized plan for withdrawal. They can provide personalized recommendations based on your specific circumstances and help minimize the potential risks associated with withdrawal.

Understanding the withdrawal process and having a healthcare professional's guidance can greatly contribute to a smoother transition off Seroquel. By managing the withdrawal symptoms effectively, individuals can navigate this phase with greater comfort and support.

Misuse and Abuse of Seroquel

While Seroquel (quetiapine) is primarily prescribed to treat certain mental health conditions, misuse and abuse of this medication have become a growing concern. Understanding the signs of abuse and the risks associated with misuse is essential for promoting safe and responsible medication use.

Signs of Abuse

Quetiapine abuse is often motivated by its sedative and anxiolytic (anxiety-reducing) effects, rather than seeking euphoric sensations. Individuals may misuse Seroquel as a form of self-medication for symptoms of anxiety and sleep withdrawal [3]. Some common signs of Seroquel abuse include:

Taking higher doses than prescribed or taking it without a prescription
Using Seroquel for non-medical purposes, such as to induce sleep or relaxation
Combining Seroquel with other substances, such as alcohol or illicit drugs, to enhance its effects
Seeking multiple prescriptions from different healthcare providers
Engaging in doctor-shopping or prescription forgery to obtain Seroquel

It's important to note that Seroquel misuse and abuse can have serious consequences, both physically and mentally. If you suspect someone may be abusing Seroquel, it is crucial to encourage them to seek help from a healthcare professional.

Risks of Misuse

Misuse of Seroquel can lead to various health risks and complications. Quetiapine is increasingly being misused due to its anxiolytic and sedative effects, as clinicians are prescribing fewer benzodiazepines and other addictive substances. Some potential risks of Seroquel misuse include:

Sedation and excessive drowsiness, which can impair one's ability to function normally
Cardiovascular effects such as low blood pressure and irregular heartbeat
Respiratory depression, which can be life-threatening if severe
Seizures, especially when high doses are taken or when Seroquel is used with other substances
Increased risk of accidents or falls due to impaired coordination and judgment

It's crucial to recognize that Seroquel is a powerful medication and should only be taken as prescribed by a healthcare professional. Using Seroquel recreationally or without medical supervision can have severe consequences. If you or someone you know is struggling with substance abuse involving Seroquel, seek immediate help from a healthcare provider or contact a substance abuse hotline for guidance.

To learn more about the effects of Seroquel on a normal person and its classification as a controlled substance, refer to our articles on effects of Seroquel on a normal person and is Seroquel a controlled substance?.

Long-Term Effects of Seroquel

As with any medication, it is important to understand the potential long-term effects of Seroquel. Seroquel, also known as quetiapine, is a medication commonly prescribed to treat mental health conditions such as schizophrenia and bipolar disorder. While it can be beneficial for many individuals, it is essential to be aware of the potential physical and psychological effects that may arise from long-term use.

Physical Effects

Long-term use of Seroquel has been associated with several physical effects. One of the most common concerns is weight gain, which has been reported by many individuals taking Seroquel. This weight gain can be accompanied by related conditions such as high blood sugar, diabetes, high triglycerides, and high cholesterol. It is important for individuals on long-term Seroquel treatment to monitor their weight and discuss any concerns with their healthcare provider.

Additionally, Seroquel has been associated with an increased risk of certain muscle problems. These include extrapyramidal symptoms (EPS), which can lead to stiffness and involuntary muscle movements, and tardive dyskinesia (TD), which involves constant involuntary movement, especially in the mouth [4]. Regular monitoring of muscle function and reporting any unusual symptoms to a healthcare professional is crucial for those taking Seroquel long-term.

Another significant concern related to long-term Seroquel use is the potential risk of cardiovascular issues. Studies have shown that individuals taking quetiapine, the active ingredient in Seroquel, may have an increased risk of stroke. Additionally, antipsychotic medications like Seroquel are associated with an elevated risk of cardiac-related complications, which can lead to disability or even death [4]. It is important for individuals on long-term Seroquel treatment to be aware of these potential risks and to discuss them with their healthcare provider.

Psychological Effects

In addition to the physical effects, Seroquel can also have psychological effects when used long-term. While Seroquel is primarily prescribed to manage symptoms of mental health conditions, there is a possibility of certain psychological effects arising from extended use. It is crucial to note that the specific effects may vary from person to person.

Long-term use of Seroquel may be associated with changes in mood, cognition, and overall mental well-being. These effects can include feelings of sedation, drowsiness, or mental clouding. It is important to communicate any changes in mood or cognitive function to a healthcare professional to ensure appropriate monitoring and management.

It is worth noting that the effects mentioned above are potential risks associated with long-term use of Seroquel. The specific impact on an individual can vary based on factors such as dosage, duration of use, and individual susceptibility. Regular communication with a healthcare provider is essential to assess and manage any potential long-term effects of Seroquel use.

For more information on Seroquel and its effects, please refer to our articles on effects of Seroquel on a normal person, is Seroquel a controlled substance?, and Seroquel abuse: what to know.

Overdose and Emergency Response

While Seroquel is generally a safe and effective medication when used as prescribed, it is important to be aware of the potential risks of overdose. In the event of an overdose, prompt medical attention is crucial. This section will address the symptoms of Seroquel overdose and the appropriate emergency protocol to follow.

Symptoms of Overdose

Signs of a Seroquel overdose may vary depending on the individual and the amount of the drug consumed. Common symptoms of an overdose may include:

Drowsiness
Rapid heart rate
Low blood pressure
Fainting
Seizures
Coma

It is important to note that the risk of overdose or toxicity is higher when Seroquel is taken in larger doses than prescribed. If you suspect an overdose or notice any of these symptoms, seek immediate medical assistance. Contact emergency services or your local poison control center for guidance.

Emergency Protocol

In the case of a Seroquel overdose, it is crucial to seek medical help without delay. The following steps outline the emergency protocol to follow:

Call emergency services: Dial your local emergency number (e.g., 911 in the United States) to report the overdose and provide them with all relevant information.
Stay with the person: If someone has overdosed on Seroquel, it is important to stay with them until medical professionals arrive. Provide reassurance and monitor their breathing and consciousness level.
Do not induce vomiting: Unless instructed to do so by a medical professional or poison control, it is generally advised not to induce vomiting in cases of Seroquel overdose.
Cooperate with medical professionals: When emergency medical services arrive, provide them with accurate information about the situation and any details pertaining to the overdose. This will assist them in providing appropriate care.

Remember, there is no specific antidote for Seroquel overdose. Therefore, seeking immediate medical attention is vital to ensure the best possible outcome.

Understanding the risks associated with Seroquel, including the potential for overdose, is essential in promoting safe and responsible use of the medication. If you have any concerns or questions about Seroquel or its effects, consult with a healthcare professional.