Seroquel Abuse: What to Know

Discover the alarming truth about Seroquel abuse: know the risks, signs, and consequences. Stay informed, Ohio!

Leora B.H. Staff

July 31, 2024

Understanding Seroquel

Seroquel, also known by its generic name quetiapine, is a medication used to treat certain mental and mood disorders, such as schizophrenia, bipolar disorder, and sudden episodes of mania or depression associated with bipolar disorder. It belongs to a class of drugs known as atypical antipsychotics.

Purpose and Usage

The purpose of Seroquel is to help manage the symptoms of mental and mood disorders. It is commonly prescribed to individuals diagnosed with schizophrenia, bipolar disorder, and major depressive disorder. Seroquel works by affecting the balance of certain neurotransmitters in the brain, including dopamine and serotonin, which play a role in regulating mood and behavior.

Seroquel is typically prescribed as part of a comprehensive treatment plan that may include therapy, counseling, and lifestyle modifications. The dosage and duration of treatment will vary depending on the specific condition being treated and the individual's response to the medication.

Drug Class and Availability

Seroquel belongs to the class of medications known as atypical antipsychotics. These medications differ from older, typical antipsychotics in their mechanism of action and potential side effects. Atypical antipsychotics are considered to have a lower risk of causing movement disorders, such as tardive dyskinesia, compared to typical antipsychotics.

Seroquel is available in various forms, including immediate-release tablets and extended-release tablets. The immediate-release tablets are typically taken two to three times a day, while the extended-release tablets are taken once daily. The availability of Seroquel may vary depending on the country and local regulations.

It's important to note that Seroquel is a prescription medication and should only be used under the guidance and supervision of a healthcare professional. It is not available over-the-counter.

Understanding the purpose, usage, drug class, and availability of Seroquel provides a foundation for further exploration of its potential side effects, dosage guidelines, and risks associated with its use. For more information on the side effects and risks of Seroquel, refer to the respective sections in this article.

Side Effects of Seroquel

As with any medication, Seroquel (generic name: quetiapine) may cause certain side effects. It's important to be aware of both the common and serious side effects associated with this medication. If you experience any concerning side effects, it's crucial to seek medical attention.

Common Side Effects

Some common side effects of Seroquel include:

Constipation
Drowsiness
Upset stomach
Tiredness
Weight gain
Blurred vision
Dry mouth
Dizziness
Lightheadedness

While these side effects are generally mild and may not require medical intervention, it's still important to discuss them with your healthcare provider if they persist or become bothersome. It's worth noting that individual experiences with side effects may vary.

Serious Side Effects

In addition to the common side effects, Seroquel can also cause more serious side effects that require immediate medical attention. These may include:

Constipation with abdominal pain
Mental/mood changes
Difficulty swallowing
Loss of appetite
Yellowing of the eyes/skin (jaundice)
Interrupted breathing during sleep
Trouble urinating
Fainting
Seizure
Severe dizziness

If you experience any of these serious side effects, it's crucial to seek medical assistance promptly. It's important to note that this list is not exhaustive, and other serious side effects may occur. It's always best to consult with your healthcare provider for a comprehensive understanding of the potential side effects of Seroquel.

It's worth mentioning that Seroquel may cause tardive dyskinesia, a movement disorder characterized by involuntary movements of the face, tongue, arms, and legs. If you notice symptoms such as lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs, it's important to inform your doctor promptly [2].

It's also worth noting that Seroquel may cause drowsiness, impaired thinking, difficulty controlling body movements, or vision changes (especially during the first week of use). These effects may increase the risk of falls, fractures, or other injuries. It's important to avoid activities such as driving or operating machinery that may be dangerous until you understand how Seroquel affects you.

If you have any concerns or questions about the side effects of Seroquel, it's essential to consult with your healthcare provider. They can provide personalized advice and guidance based on your specific situation.

Seroquel Dosage and Administration

When it comes to the dosage and administration of Seroquel, it is essential to follow the guidance of a healthcare professional. The appropriate dosage depends on various factors, including the medical condition being treated, the individual's age, and their response to the medication.

Available Strengths

Seroquel is available in six different strengths: 25 mg, 50 mg, 100 mg, 200 mg, 300 mg, and 400 mg. The specific strength prescribed by a doctor will depend on the intended use and the individual's needs.

Dosage Guidelines

Dosage guidelines for Seroquel can vary depending on the condition being treated. It is important to note that the following information is a general guideline and should not replace medical advice. Always consult with a healthcare professional for personalized dosage recommendations.

For the acute treatment of manic episodes of bipolar I disorder in adults, the typical starting dose of Seroquel is lower and gradually increased over the first four days of treatment. The maintenance dosage is usually between 400 mg and 800 mg per day.

For the treatment of schizophrenia in adults, the recommended starting dose is typically 25 mg twice daily. The dosage may be increased gradually, with the target dose ranging from 300 mg to 400 mg per day (divided into two or three doses) for most patients. However, some individuals may require higher doses.

Dosage adjustments may be necessary for individuals with liver or kidney problems, as well as for elderly patients. It is important to follow the guidance of a healthcare professional to ensure the appropriate dosage is prescribed.

It is crucial to adhere to the prescribed dosage and not exceed the recommended amount. Taking higher doses or using Seroquel in ways other than prescribed can lead to serious health risks and consequences. If you have any concerns or questions about your Seroquel dosage, consult your healthcare provider for clarification.

Understanding the proper dosage and administration of Seroquel is crucial for ensuring safe and effective treatment. It is important to communicate openly with your healthcare provider about any side effects or concerns you may have during your treatment with Seroquel.

Risks and Warnings

When considering the use of Seroquel, it's important to be aware of the risks and warnings associated with this medication. Understanding the FDA approval and indications, as well as special populations who may require additional caution, can help ensure the safe and appropriate use of Seroquel.

FDA Approval and Indications

Seroquel, also known as quetiapine, is FDA-approved to treat schizophrenia in adults and children aged 13 and older, as well as certain types of bipolar disorder [3]. It is also used in combination with other medications to treat major depressive disorder. However, certain age groups have not been extensively studied for safety and efficacy. Appropriate studies have not been performed to establish the use of quetiapine in children with schizophrenia younger than 13 years old, children with bipolar mania younger than 10 years old, and children with bipolar depression. Therefore, caution should be exercised when considering the use of Seroquel in these age groups.

Special Populations

Certain populations may require special considerations when using Seroquel. It is important to note that Seroquel should not be shared with others, as it is tailored to the specific needs and conditions of the individual. Additionally, medical tests should be conducted before and during the use of Seroquel to monitor various aspects of health, including blood sugar, blood pressure, cholesterol levels, eye health, weight, and blood counts.

In females, the use of quetiapine may lead to unwanted side effects such as unwanted breast milk, missed or stopped periods, or difficulty becoming pregnant. In males, it may cause decreased sexual ability, inability to produce sperm, or enlarged breasts. Rarely, males may experience a painful or prolonged erection lasting four or more hours, which requires immediate medical attention to prevent permanent problems [1].

For older adult patients who have dementia or Alzheimer's disease, Seroquel should not be used to treat behavioral problems, as it may increase the risk of death. It is important to consult with a healthcare professional to determine the appropriate course of treatment for these conditions.

Being aware of the FDA approval and indications, as well as the considerations for special populations, can help individuals make informed decisions about the use of Seroquel. It is important to follow the guidance of healthcare professionals and undergo regular medical monitoring to ensure the safe and effective use of this medication.

Signs of Seroquel Abuse

Recognizing the signs of Seroquel abuse is crucial in order to address the issue and provide appropriate support. Abuse of Seroquel, also known by its generic name quetiapine, can have serious consequences for an individual's physical and mental well-being. In this section, we will explore the physical and mental signs that may indicate Seroquel abuse.

Physical Signs

Physical signs of Seroquel abuse can vary depending on the method of administration. If an individual is abusing Seroquel through intravenous injection, they may exhibit signs such as skin infections at the injection site, track marks, and the presence of paraphernalia like rubber hoses, needles, and dirty spoons [4].

Other physical signs associated with Seroquel abuse include redness or dryness around the nose, constant sniffing or nasal congestion, sore throat, hoarse voice, and coughing. These signs may indicate that an individual is misusing Seroquel or using it in higher doses than prescribed.

Mental Signs

Alongside the physical signs, there are also mental signs that may indicate Seroquel abuse. These can include confusion, agitation, hallucinations, delusions, and even suicidal thoughts. It is important to note that these mental side effects may be more prevalent in individuals who are not prescribed Seroquel or are using it outside of the recommended dosage.

Other mental signs associated with Seroquel abuse can include needing frequent refills, stealing the drug, stealing money for the drug, or experiencing financial, legal, or social ramifications due to being intoxicated. These signs may indicate a problematic pattern of Seroquel misuse that requires intervention and support.

Recognizing the signs of Seroquel abuse is the first step towards helping individuals who may be struggling with this issue. If you suspect that someone may be misusing or abusing Seroquel, it is important to encourage them to seek professional help and support. Early intervention can make a significant difference in preventing further harm and promoting recovery.

For more information on the effects of Seroquel on a normal person, the controlled substance status of Seroquel, and understanding the concept of a Seroquel high, please refer to our related articles: effects of seroquel on a normal person, is seroquel a controlled substance?, and understanding seroquel high.

Consequences of Seroquel Abuse

When Seroquel is abused, it can lead to various negative consequences and pose significant risks to the individual's health. Two key consequences of Seroquel abuse are toxicity and overdose, along with broader public health implications.

Toxicity and Overdose

Abusing Seroquel by taking it in larger doses than prescribed or using it in ways other than intended can lead to toxicity and overdose. Signs of Seroquel toxicity include rapid heart rate, low blood pressure, drowsiness, and seizures. It is important to note that the risk of overdose or toxicity is higher when Seroquel is misused or taken in larger quantities than prescribed.

Overdosing on Seroquel can have severe consequences and may require immediate medical attention. If you suspect an overdose or experience symptoms of Seroquel toxicity, it is crucial to seek emergency medical help.

Public Health Implications

The misuse and abuse of Seroquel, particularly in the context of other atypical antipsychotics, present public health challenges. Quetiapine, the active ingredient in Seroquel, has become the most commonly abused atypical antipsychotic. This abuse occurs not only in penal populations but also among psychiatric inpatients, outpatients, and patients attending drug treatment clinics.

The misuse and abuse of Seroquel have negative health consequences and can result in emergency department visits. These incidents place a strain on mental health budgets and public health resources. To address this rising problem, tighter regulations and clinical guidelines may be necessary to curb the misuse of Seroquel and other atypical antipsychotics.

Understanding the potential consequences of Seroquel abuse is crucial for individuals who may be at risk. It is important to seek help and support from healthcare professionals if you or someone you know is struggling with Seroquel abuse. Proper education, awareness, and access to appropriate treatment are vital in addressing the public health implications associated with Seroquel misuse.

To learn more about the effects of Seroquel on a normal person and whether it is a controlled substance, refer to our articles on effects of Seroquel on a normal person and is Seroquel a controlled substance?.